Point-of-Care Testing Based on Electrochemical Sensing

Disposable microfluidic cartridge with integrated electrochemical biosensor allows for quantitative, high sensitivity measurement of antigen biomarker concentration.

The Application

Point-of-care (POC) diagnostics testing is an important part of the healthcare workflow worldwide.  Many disease associated biomarkers require high accuracy quantitative measurements.

The Challenge

Low-cost lateral flow devices can only provide semi-quantitative measurements.  An alternative platform for low-cost, high accuracy disposable POC testing is needed.

The Solution

The Result

Using commercial Procalcitonin (PCT) and C-reactive protein (CRP) ELISA assay kits on our platform, we demonstrated:

  • Quantitative antigen detection to below 100pg/ml level

  • Screen-printed electrodes designed for protein surface immobilization and performing parallel control assays

  • Fully integrated microfluidic flow cells for automated assay testing and optimization

Please contact us if you are interested in partnership development using our platform.

Wainamics developed a universal POC platform that allows for quantitative, high-sensitivity immunoassay measurements using low-cost disposable cartridges.  By incorporating electrochemical detection with a microfluidic cartridge, this platform enables rapid development of point-of-care testing cartridges using established assay kits.